If you have Microsoft Office installed on MacOS, you gotta deal with Microsoft AutoUpdate which pesters you every few hours to update MS Office stuff. Deleting MAU isn't a solution as it reinstalls itself later. Redditors however found a workaround for it. By disabling execution permissions and not deleting MAU, one could get rid of it. Follow the commands below:
Open your terminal on MacOS and run the following commands:
$ cd /Library
$ cd 'Application Support'
$ cd /Microsoft/MAU2.0
$ sudo chmod -R a-wx "Microsoft AutoUpdate.app"
Thats it, you disable the execution permissions and MAU will no longer bother